This may be the liquor store closest to Fenway Park, steer clear on game days.

Copperfield's, located on Brookline Ave just a stone's throw from Fenway Park, is a great alternative to the more popular Game On! and Cask and Flagon. The ambiance of Copperfield's may not stand up to its more polished competitors, but where Copperfield's lacks in aesthetic charm it compensates for in great service. While your buddies are vying for a barstool before or after a Sox game, you can show them how savvy you are by easily snagging a comfortable seat (and several beers) at Copperfield's. They might not be impressed with the dungeon-like decor, but they'll certainly be glad that you've found someplace to drink that doesn't involve battling tourist and fans for a place to stand.
If you're looking for a quick bite to eat and some passable pub grub Copperfield's isn't your place. This bar only serves beverages.
Open weekdays from Noon-2am. Hours vary on game days.

This is the local "packy" (package store) for the folks on Queensberry and Jersey Streets. Jersey Street Liquors is pretty standard as beer, wine, and liquor selection goes. If you're looking for any spirit that might be considered hard to find, you can bet that this location won't have it.
That being said, that doesn't mean that Jersey Street liquors is inadequate. The location is small, clean, and incredibly convenient if you live in the Queensbury/Peterborough area.

This neighborhood trattoria offers up Italian food from their cucina and a selection of vino to accompany it. It's a small, local restaurant with around ten tables. Trattoria Toscana might not be aesthetically impressive on the outside, but the inside of the building is decorated warmly and tastefully. Entrees range from $15-$22 and include various combinations of pasta with chicken, seafood, or sausage and the house's many unique sauces. The wine list is extensive to compliment all the complex flavors on their menu. What the trattoria lacks in size it compensates for in service. Due to its small size, the waiters are a tight-knit group of seasoned waiters who excel at their jobs. There's no doubt that Trattoria Toscana is a wonderful hidden gem in the heart of the Fenway.

A bar on the edge of Fenway Park's outfield. You enter from Lansdowne Street, but a large window in the sitting area allows diners and drinkers to peer out onto the field to watch the games. According to BU Today, there's "no nachos, no chicken wings, no quesadillas," so don't expect typical bar fair; "high-end," classic sandwiches like "pastrami, salami, beef brisket, corned beef, liverwurst.... turkey club, grilled cheese with bacon, and 'sliders'" make up the better part of the menu's hearty choices. Click here to view their menu. On tap: Bud, Miller Light and Sam Seasonal.